Authors and affiliations: Macedo JA, Hesse J, Turner JD, Ammerlaan W, Gierens A, Hellhammer DH, Muller CP. Institute of Immunology, Laboratoire National de Santé, Luxembourg; Department of Immunology of the Graduate School of Psychobiology, University of Trier, Trier, Germany.
L-selectin was elevated on monocytes and neutrophils of FM patients. Differences in group response to DEX were observed for CD11b on NK cells, sICAM-1 and IL-2. [L-selectin is a cell adhesion molecule found on white blood cells (leukocytes) said to act as a "homing receptor" for them to enter tissues at the site of inflammation. Monocytes and neutrophils are two types of white blood cells.]
This study shows a slight disturbance in the innate immune system of FM patients, and suggests an enhanced adhesion and recruitment of leukocytes to inflammatory sites.